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Intervention 1: erythromycin base, 500 mg oral 3 times daily for 5 days (69 participants). All participants were asked to refrain from sexual contact and to return for follow‐up examinations between day 7 and day 10 following initiation of therapy and approximately 1 week later (days 14‐21). Blood was obtained by venepuncture for syphilis (RPR and FT A‐Abs tests) and chlamydial micro‐IF serology. Swabs were also taken directly from lesions for isolation of C trachomatis and HSV. After material had was obtained for darkfield microscopy, swabs were taken for isolation of H ducreyi from the bases of lesions and, where applicable, aspirates were obtained from fluctuant lymph nodes. The characteristics of any associated inguinal or femoral lymphadenopathy were recorded. Genital examination performed, and presence and clinical details of any genital ulceration noted.

In addition, they had to be available for follow‐up examination and should not have received any antimicrobial chemotherapy during the preceding 7 daysĮxclusion criteria: People were subsequently excluded if either HSV or Chlamydia trachomatis were isolated from their lesions, or if attempts to isolate Haemophilus ducreyi from genital lesions at the initial visit were unsuccessful.īaseline characteristics: aetiological diagnose. Participants were included if dark‐field examination proved to be negative for Treponema pallidum. If there was > 1 ulcer, the largest ulcer was selected for study.

painful, non‐indurated lesions with purulent bases. Inclusion criteria: migrant mine workers with genital ulcers consistent with a clinical diagnosis of chancroid, i.e.

Descargar libro florez farmacologia humana 5ta edicion trial#

Trial design: single‐centre, parallel, randomized controlled trial, 2 arms.Įthical issues: ethical board and signed consent.

Descargar libro florez farmacologia humana 5ta edicion how to#

Learn how to connect your accounts.Setting: South Africa, outpatient clinic.

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